Professor Khong, Pek-Lan
MBBS, M.D., FRCR(UK), FHKCR, FHKAM (Radiology) 
Professor, Head of Department of Diagnostic Radiology, HKU
Honorary Consultant Radiologist, Department of Radiology, QueenMaryHospital, Hong Kong
E-mail : 

Research Interest 
1. General Paediatric Radiology, including perinatal and neonatal imaging.
2. Paediatric Neuroradiology, in particular, applications of advanced MR imaging modalities, including Diffusion-weighted imaging, 
    Diffusion tensor imaging and Magnetic Resonance, Spectroscopy and fMRI.
3. Adult and Paediatric Oncology and Haematology, including applications of PET-CT imaging.
4. Animal MR imaging; translational research in animal models.

Selected Publications     
  1. Khong PL, Goh WHS, Wong VCN, Fung CW, Ooi GC.MR imaging of spinal tumors in children with Neurofibromatosis-1.American Journal of Roentgenology 2003;180:413-417.
  2. Khong PL, Lam BCC, Chung BHY, Wong KY, Ooi CGC.Diffusion weighted MR imaging in neonatal non-ketotic hyperglycinemia.American Journal of Neuroradiology 2003;24:1181-1183.
  3. Khong PL, Kwong DLW, Chan GCF, Sham JST, ChanFL, Ooi GC.Diffusion-tensor imaging (DTI) for the detection and quantification of treatment-induced white matter injury in children with medulloblastoma: a pilot study.American Journal of Neuroradiology 2003;24:734-740.
  4. Khong PL, Lam BCC, Chung BHY, Wong KY, Ooi CGC.Diffusion weighted MR imaging in neonatal non-ketotic hyperglycinemia.American Journal of Neuroradiology 2003;24:1181-1183.
  5. Khong PL, Chan GCF, Lee SL, Au WY, Fong DYT, Tsang KWT, Ooi GC.b-Thalassemia Major: Thin-sectionCTfeatures and correlation with pulmonary function and iron overload.Radiology 2003;229:507-512.
  6. Leung LHT, Ooi GC, Kwong DLW, Chan GCF, Cao G, Khong PL.White-matter diffusion anisotropy after chemo-irradiation: a statistical parametric mapping study and histogram analysis.NeuroImage 2004;21:261-268.
  7. Khong PL, Lam CCB, Cheung PT, Goh WHS, Wong I,Tse YCC, Ooi CGC.Diffusion-weighted MR imaging (DWI) and proton-magnetic resonance spectroscopy (MRS) in perinatal hypoxic-ischaemic encephalopathy:association with neuromotor outcome at 18 months of age.Journal of Child Neurology 2004;19:872-881.
  8. Khong PL, Leung LHT, Chan GCF, Kwong DLW, Wong WHS, Cao G, Ooi GC.White matter anisotropy in childhood medulloblastoma survivors: association with neurotoxicity risk factors.Radiology 2005;236:647-652.
  9. Wang YX, Cheung PT, Shen GX, Wu EX, Cao G, Bhatia I, Wong WHS, Khong PL.Hypoxic-ischemic brain injury in the neonatal rat model: relationship between lesion size at early MR imaging and irreversible infarction.American Journal of Neuroradiology 2006;27:51-54.
  10. Khong PL, Leung LHT, Fung ASM, Fong DYT, Qiu D,Kwong DLW, Ooi GC, McAlanon G, Cao G, Chan GCF. White matter anisotropy in post-treatment childhood cancer survivors: preliminary evidence of association with neurocognitive function.Journal of Clinical Oncology 2006;24:884-890.
  11. Qiu DQ, Leung LHT, Kwong DLW, Chan GCF, Khong PL.Mapping radiation dose distribution on the Fractional Anisotropy Map: Applications in the assessment of treatment-induced white matter injury.NeuroImage 2006;31:109-115.
  12. Wang Y, Cheung PT, Shen GX, Bhatia I, Wu EX, Qiu D, Khong PL.Comparing diffusion-weighted and T2-weighted MR imaging for the quantification of infarct size in a neonatal rat hypoxic-ischemic model at 24 hours post-injury.International Journal of Developmental Neuroscience 2007;25:1-5.
  13. Yung A, Poon G, Qiu DQ, Chu J, Lam B, Leung C, Goh W, Khong PL.White matter volume and anisotropy in preterm children: a pilot study of neurocognitive correlates.Pediatric Research 2007;61:732-736.
  14. Qiu DQ, Kwong DLW, Chan GCF, Leung LHT, Khong PL. Diffusion tensor MR imaging finding of discrepant fractional anisotropy between the frontal and parietal lobes after whole-brain irradiation in childhood medulloblastoma survivors: reflection of regional white matter radiosensitivity? Internal Journal of Radiation Oncology Biology Physics 2007;69:846-851.
  15. Wang SL, Wu EX, Tam CN, Lau HF, Cheung PT, Khong PL. Characterization of white matter injury in a hypoxic-ischemic neonatal rat model by diffusion tensor MR imaging. Stroke 2008;39:2348-2353.
  16. Qiu DQ, Tan LH, Zhou K, Khong PL. Diffusion tensor imaging of normal white matter maturation from late childhood to young adulthood: voxel-wise evaluation of mean diffusivity, fractional anisotropy, radial and axial diffusivities, and correlationwith reading development. NeuroImage. 2008;41:223-232.
  17. Khong PL, Pang CBY, Liang R, Kwong YL, Au WY. Fluorine-18 fluorodeoxyglucose positron emission tomography in mature T-cell and natural killer cell malignancies. Annals of Hematology. 2008;87:613-621.
  18. Wang S, Wu EX, Qiu D, Leung LHT, Lau HF, Khong PL. Longitudinal diffusion tensor magnetic resonance imaging study of radiation induced white matter damage in a rat model. Cancer Research 2009;69:1190-1198.
  19. Chan WKS, Tse EWC, Fan PYS, Zhang J, Kwong YL, Khong PL. Positron emission tomography/computed tomography in the diagnosis of multifocal primary hepatic lymphoma. Journal of Clinical Oncology 2008 Nov 20;26(33):5479-80.
  20. Huang BS, Law MWM, Khong PL. Whole body PET-CT scan: estimation of radiation dose and cancer risk. Radiology 2009 Apr;251(1):166-74.
  21. Huang BS, Law MWM, Mak HKF, Kwok SPF, Khong PL. Pediatric CT coronary angiography using 64-slice CT with ECG-modulated tube current: radiation dose and cancer risk. American Journal of Roentgenology (in press).
Copyright@2008 The University of Hong Kong